Open Orphan #ORPH: The Times – Inside Story of coronavirus battlers. The Sun – We salute the unsung key workers. April 27, 2020 – Posted in: Open Orphan (ORPH)

Inside stories of coronavirus battlers Aerogen, Hibergene, Open Orphan and Nearform Ireland was placed sixth last week in a list of nations ranked on their response to the Covid-19 crisis in terms of innovation. The league table was compiled by StartupBlink, a Swiss-Israeli company that collates data on start-ups; the United Nations-backed Health Innovation Index; the Moscow Agency of Innovations; and partners such as tech database provider Crunchbase. While the Republic has punched above its…

Open Orphan #ORPH – Testing of anti-viral for treating COVID-19 underway April 23, 2020 – Posted in: Open Orphan (ORPH)

Open Orphan plc (ORPH) the rapidly growing specialist CRO pharmaceutical services company which has a focus on orphan drugs and is a world leader in the provision of virology and vaccine challenge study services, is pleased to announce that its London-based subsidiary hVIVO has commenced the testing of an anti-viral for treating COVID-19 on behalf of its client Nearmedic International Ltd. hVIVO has initiated work on this contract with Nearmedic International Ltd, a specialist pharmaceutical, biotechnological…

Race to stop the world getting sick: As coronavirus ravages the globe, experts work around the clock developing vaccines and trialling drugs in a desperate attempt to contain it March 24, 2020 – Posted in: Open Orphan (ORPH)

by Pat Hagan, Daily Mail As the needle slipped into Jennifer Haller’s arm, the world watched and held its breath. This was the moment last week when Jennifer became the first person to be injected with an experimental vaccine that scientists hope will help prevent future pandemics of the deadly Covid-19 coronavirus. Mother-of-two Jennifer, 43, from Seattle, told reporters: ‘We all feel so helpless. But this is an amazing opportunity for me to do something.’…

Wanted: People Willing to Get Sick to Find Coronavirus Vaccine March 19, 2020 – Posted in: Open Orphan (ORPH)

British lab is recruiting volunteers for study it says could speed development of Covid-19 vaccine By Denise Roland March 19, 2020 7:00 am ET Thousands of people have volunteered to be infected in the hope of finding a vaccine for the new coronavirus. hVIVO, a clinical research group in London, has attracted more than 20,000 volunteers willing to be infected with tamer relatives of the virus that causes Covid-19 in exchange for a fee of…

Open Orphan #ORPH – Publication of positive FLU-v vaccine challenge study results in journal March 16, 2020 – Posted in: Open Orphan (ORPH)

Positive results from FLU-v vaccine challenge study (FLU-v 004), the second Phase IIb study of FLU-v, which has been developed by Imutex Limited, hVIVO’s 49% joint venture with the SEEK Group, have now been published in a peer review journal FLU-v is a first-in-class ‘universal’, broad spectrum, standalone, influenza vaccine candidate The publication in ‘npj Vaccines’ reported that one dose of FLU-v induced statistically significant reduction in mild to moderate influenza disease (MMID) defined as detection…

Daily Mirror – Coronavirus: Inside UK clinic where volunteers get paid up to £4,000 to be infected in race to find vaccine March 12, 2020 – Posted in: Open Orphan (ORPH)

by Rhian Lubin EXCLUSIVE: Infecting volunteers so they can be tested could help stop the spread of Covid-19 – so now 24 triallists face 14 days of solitary confinement and we took a look inside. As I lie in a hospital bed in a sterile clinic room, a nurse in blue scrubs with a full face shield and ventilator peers through the glass. The red tape around the door makes it crystal clear that this…

BRR Media – Cathal Friel & hVIVO Chief Scientist Andrew Catchpole discuss the Coronavirus Challenge Study and the FLU-V Vaccine – Posted in: Open Orphan (ORPH)

Cathal Friel & hVIVO Chief Scientist Andrew Catchpole discuss recent developments and the Coronavirus Challenge Study and the FLU-V Vaccine with the BRR Media team.

Proactive Investors – Open Orphan #ORPH catching global attention with ‘stunning’ FLU-v results & world-first coronavirus study – Posted in: Open Orphan (ORPH)

Open Orphan PLC‘s (LON:ORPH) Cathal Friel and its subsidiary hVIVO’s chief scientist Dr Andrew Catchpole sat down with Proactive London’s Andrew Scott. This morning Open Orphan announced the results from a clinical trial of a broad-spectrum flu jab that they’re jointly developing have been published in a peer-reviewed journal. The data from the FLU-v 003 phase IIb study of the FLU-v vaccine appeared in the Annals of Internal Medicine periodical. Also this week hVIVO began…

Open Orphan #ORPH – Development of the World’s First Human Coronavirus Challenge Study Model March 9, 2020 – Posted in: Open Orphan (ORPH)

Open Orphan, the rapidly growing specialist Clinical Research Organisation (“CRO”) pharmaceutical services company whose London-based subsidiary hVIVO is the world leader in the provision of virology and vaccine challenge study services, is pleased to announce that it has commenced the development of the world’s first commercial human coronavirus challenge study model, also known as a Controlled Human Infection Model (CHIM). The Company has Europe’s only 24-bedroom quarantine clinic with onsite virology lab where the challenge model…

Sunday Times – Coronavirus vaccine race: volunteers to be infected in the UK March 8, 2020 – Posted in: Open Orphan (ORPH)

Human guinea pigs in a London lab are to be given a form of the killer virus as the search for a lucrative jab hots up It sounds tempting: a payment of £3,500 to spend two weeks relaxing in front of the television, playing video games or catching up on some reading. There is a catch, however — you will be infected with a coronavirus and banned from physical contact with the outside world. As…